ATW0008 - Fibronectin Aptamer

ATW0008
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Target:   Fibronectin

Target Species:   bovine, human

Target Type:   protein

Affinity Constant (Kd):   1.7 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

*Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

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ATW0008 Aptamer to Human and Bovine Fibronectin Protein

Fibronectin is a high-molecular weight (~440kDa) glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans (e.g. syndecans).

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and Fibronectin from bovine plasma, [Sigma Cat #F4759] but was also affinity tested with human plasma fibronectin, Advanced BioMatrix, San Diego, CA [Part No. 5050] as a target. Both selection and validations were conducted in 20 mM Tris, 100 mM NaCl, 0.005% Tween20 in nuclease free water, pH 7.4.

View Data Sheet

Fibronectin Aptamer ATW0008 Data Sheet_May2018 [Download]

Base Pair Biotechnologies Aptamers Combined with Vista Therapeutics NanoBioSensors for Biomarker Measurement in Human Serum [Download]