ATW0022 - IL-18 Aptamer

ATW0022
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Target:   IL-18 (Interleukin-18)

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   20.4 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

*Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

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ATW0022 Aptamer to Human Interleukin-18 (IL-18)• Cytokine. Interleukin-18 (IL-18)• is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. IL-18 works by binding to the interleukin-18 receptor, and together with IL-12 it induces cell-mediated immunity following infection with microbial products like lipopolysaccharide (LPS). After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFNγ) or type II interferon that plays an important role in activating the macrophages or other cells. This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods,• Human Interleukin-18, [Novus Biologicals, Cat #NBC1-20152]

View IL-18 Aptamer Data Sheet•

ATW0022 IL18 Data Sheet [Download]