ATW0049 - Alpha-Methylacyl-CoA Racemase (AMACR) Aptamer

ATW0049
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Target:   AMACR

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   2278 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

*Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

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Alpha-Methylacyl-CoA Racemase, AMACR, is an enzyme found in mitochondria and peroxisomes within the cell. It is required for beta oxidation / breakdown of branched-chain fatty acids and bile acid intermediates. AMACR deficiency has been linked to pigmentary retinopathy and adrenomyeloneuropathy. AMACR is overexpressed in prostate cancer.

https://www.omim..org/entry/604489

ATW0049 AMACR Data Sheet [Download]