Aptamers offer solutions to many scientific challenges other reagents can’t overcome. Learn More.
Pursue Toxic and Non-immunogenic TargetsOvercome antibody host toxicity or failure to generate an antibody response
Target Small MoleculesBind molecules ≥ ~60 daltons, 10-fold smaller than the smallest Ab targets
Design Stable Molecular “Switches”Simplify assay design or modulate therapeutic function
Penetrate Tissues and CellsTarget intracellular proteins; access solid tumors
Perform Simple Chemical ModificationsEnhance affinity, stability, solubility or detection
Improve Reproducibility and StabilityEasily synthesize and re-fold aptamers
Partnering with Base Pair
Every project is unique. Base Pair scientists work closely with each client to understand project objectives, identify technical challenges, and provide innovative aptamer-based solutions. Learn More.
We take the time to fully understand customer needs and address project challenges
Every project is carefully designed from classic and novel options for selection and optimization
Multiplex SELEX™ , proprietary selection algorithms and characterization techniques
True success is defined by aptamer performance in real-world applications
Aptamer Discovery and Development with Base Pair
At Base Pair, each phase of every project is designed to have the highest likelihood of functional success. Learn More
Phase 1: ConsultNeeds Definition
Phase 2: DesignLibrary Selection
Phase 3: SelectSELEX
Next Gen Sequencing
Phase 4: ScreenHigh Throughput Screening
Phase 5: Apply & EvaluateAssay Feasibility
Phase 6: MatureTruncation
Let Base Pair design an aptamer selection strategy for your application.