Why Aptamers?

Aptamers offer solutions to many scientific challenges other reagents can’t overcome. Learn More.

Pursue Toxic and Non-immunogenic Targets
Overcome antibody host toxicity or failure to generate an antibody response
Target Small Molecules
Bind molecules ≥ ~60 daltons, 10-fold smaller than the smallest Ab targets
Design Stable Molecular “Switches”
Simplify assay design or modulate therapeutic function
Penetrate Tissues and Cells
Target intracellular proteins; access solid tumors
Perform Simple Chemical Modifications
Enhance affinity, stability, solubility or detection
Improve Reproducibility and Stability
Easily synthesize and re-fold aptamers

Partnering with Base Pair

Every project is unique. Base Pair scientists work closely with each client to understand project objectives, identify technical challenges, and provide innovative aptamer-based solutions. Learn More.

Consultative Approach

We take the time to fully understand customer needs and address project challenges

Customized Solutions

Every project is carefully designed from classic and novel options for selection and optimization

Innovative Technology

Multiplex SELEX, proprietary selection algorithms and characterization techniques

Effective Aptamers

True success is defined by aptamer performance in real-world applications

Aptamer Discovery and Development with Base Pair

At Base Pair, each phase of every project is designed to have the highest likelihood of functional success. Learn More

Phase 1: Consult
Needs Definition
Project Scope
Phase 2: Design
Library Selection
Library Modification
Target Selection
Phase 3: Select
Next Gen Sequencing
Phase 4: Screen
High Throughput Screening
Affinity Testing
Phase 5: Apply & Evaluate
Assay Feasibility
Functional Testing
Assay Optimization
Phase 6: Mature
Base Substitution
New Functionality

Request Information

Let Base Pair design an aptamer selection strategy for your application.