Aptamers offer solutions to many scientific challenges other reagents can’t overcome. Learn More.
Pursue toxic and non-immunogenic targetsOvercome antibody host toxicity or failure to generate an antibody response
Target small moleculesBind molecules ≥ ~60 daltons, 10-fold smaller than the smallest Ab targets
Design stable molecular “switches”Simplify assay design or modulate therapeutic function
Penetrate tissues and cellsTarget intracellular proteins; access solid tumors
Perform simple chemical modificationsEnhance affinity, stability, solubility or detection
Improve reproducibility and stabilityEasily synthesize and re-fold aptamers
Partnering with Base Pair
Every project is unique. Base Pair scientists work closely with each client to understand project objectives, identify technical challenges, and provide innovative aptamer-based solutions. Learn More.
Consultative Approach We take the time to fully understand customer needs and address project challenges
Customized Solutions Every project is carefully designed from classic and novel options for selection and optimization
Innovative Technology Multiplex SELEX™ , proprietary selection algorithms, and more to come
Effective Aptamers True success is defined by aptamer performance in real-world applications
Aptamer Discovery and Development with Base Pair
At Base Pair Biotechnologies, each phase of every project is custom designed to have the highest likelihood of functional success. Aptamers to specific targets can often be developed in just 8-12 weeks. With Base Pair’s patented multiplex platform, aptamers to multiple targets can be selected simultaneously, significantly decreasing overall development time and cost. Additionally, our AptaTracker™ Tool enables customers to stay connected throughout each aptamer development project. Learn More.
Phase 1: Consult
Phase 2: Design
Phase 3: Select
Next Gen Sequencing
Phase 4: Screen
High Throughput Screening
Phase 5: Apply
Phase 6: Evaluate
Phase 7: Mature
Learn more about aptamer discovery with Base Pair.