In the July Issue • Attending the Immuno-Oncology Summit in Boston? Meet with Base Pair! • Immunohistochemistry with Aptamers • Immuno-Oncology and Aptamers? Attending the Immuno-Oncology Summit in Boston? Meet with Base Pair! From discovery of tumor-specific antigens through cell-SELEX to aptamer reagents for flow cytometry, cell targeting, and electrochemical detection, Base Pair offers several […]
In the May Issue • Base Pair Aptamers to Antibiotics • Discovery of Aptamers to Small Molecule Antibiotics • Aptamers and Antibiotics: Detection, Monitoring, and Continuous Dosing Base Pair Aptamers to Antibiotics Base Pair has selected natural DNA aptamers to the antibiotics ampicillin and tetracycline. Additional DNA aptamers to antibiotics are in development. […]
In the April Issue • Take the 2-Question Aptamer Topics Survey • Aptamer Selection Articles • The Anti-Viral Power of Aptamers Take the 2-Question Aptamer Topics Survey We’re planning several new feature articles on aptamers for 2019. Tell us which topics are of most interest to you. 3 lucky respondents will receive […]
In the March Issue • New! Aptamers in Drug Development Webinar • History of Aptamers and Antibodies • Aptamers in Oncology: Early Detection and Targeted Drug Delivery New! Aptamers in Drug Development Webinar Base Pair recently presented at the LabRoots virtual drug discovery conference. The latest webinar includes a review of aptamer […]
In The February Issue • New! Aptamer to DEHP • Aptamers to Metabolites of Nerve Agents Sarin and VX • Detecting Chemical Contaminants with Aptamers New! Aptamer to DEHP A selective aptamer for Di(2-ethylhexyl)phthalate, or DEHP, is now available from Base Pair. DEHP is found in many consumer products and medical devices manufactured from PVC/vinyl. Ingestion […]
In The January Issue • New! BLI Affinity Determination Service from Base Pair • Advantages of Biomarker Detection with Aptamers BLI Affinity Determination Service The determination of aptamer-target binding characteristics is an important tool in the aptamer discovery process. Bio-Layer Interferometry (BLI) calculates an association constant, dissociation constant, and affinity constant for evaluation of lead aptamer […]
In The December Issue • Aptamer Maturation: Improving Aptamer Performance • NGS and Bioinformatics Services for Aptamer Selection • Aptamers in Flow Cytometry Subscribe to the monthly Base Pair e-newsletter Aptamer Maturation: Improving Aptamer Performance A key advantage of aptamers is the ability to select aptamers in vitro for binding to difficult (non-immunogenic, toxic) targets. […]
In The November Issue • Next Gen Sequencing for Aptamer Selection • Bioinformatics Service for Aptamer Selection • Selecting Aptamers to Cells for Biomarker Discovery Subscribe to the monthly Base Pair e-newsletter Next Gen Sequencing for Aptamer Selection The introduction of next generation sequencing has enabled the analysis of millions of potential aptamer sequences […]
In The October Issue Determining Aptamer Affinity Coming Soon! Next Generation Sequencing and Bioinformatics Services Aptamers in Drug Delivery, Pharmacokinetics, and Dosing Determining Aptamer Affinity Did you miss the latest article from Base Pair? There are several popular methods for measuring biomolecular interactions and evaluating aptamer affinity. This article gives an overview of SPR, […]
In The September Issue Aptamers to Canine Cancer Biomarkers Environmental Opioid Detection Aptamers in High Resolution Microscopy Aptamers to Canine Cancer Biomarkers Comparative oncology is the study of naturally-occurring cancer in animals to identify treatments that can be applied to humans. Many types of cancer, including several types that are identical to human cancer, […]
