July Newsletter – Immuno-Oncology and Aptamers?

In the July Issue   •  Attending the Immuno-Oncology Summit in Boston? Meet with Base Pair! •  Immunohistochemistry with Aptamers  •  Immuno-Oncology and Aptamers? Attending the Immuno-Oncology Summit in Boston?   Meet with Base Pair! From discovery of tumor-specific antigens through cell-SELEX to aptamer reagents for flow cytometry, cell targeting, and electrochemical detection, Base Pair offers several […]

May Newsletter – Aptamers and Antibiotics

In the May Issue   •  Base Pair Aptamers to Antibiotics •  Discovery of Aptamers to Small Molecule Antibiotics  •  Aptamers and Antibiotics: Detection, Monitoring, and Continuous Dosing Base Pair Aptamers to Antibiotics   Base Pair has selected natural DNA aptamers to the antibiotics ampicillin and tetracycline. Additional DNA aptamers to antibiotics are in development. […]

April Newsletter – The Anti-Viral Power of Aptamers

In the April Issue   •  Take the 2-Question Aptamer Topics Survey •  Aptamer Selection Articles •  The Anti-Viral Power of Aptamers   Take the 2-Question Aptamer Topics Survey   We’re planning several new feature articles on aptamers for 2019. Tell us which topics are of most interest to you. 3 lucky respondents will receive […]

March Newsletter – Aptamers in Oncology

In the March Issue   •  New! Aptamers in Drug Development Webinar •  History of Aptamers and Antibodies •  Aptamers in Oncology: Early Detection and Targeted Drug Delivery   New! Aptamers in Drug Development Webinar   Base Pair recently presented at the LabRoots virtual drug discovery conference. The latest webinar includes a review of aptamer […]

January Newsletter – Biomarker Detection with Aptamers

In The January Issue   •  New! BLI Affinity Determination Service from Base Pair •  Advantages of Biomarker Detection with Aptamers   BLI Affinity Determination Service The determination of aptamer-target binding characteristics is an important tool in the aptamer discovery process. Bio-Layer Interferometry (BLI) calculates an association constant, dissociation constant, and affinity constant for evaluation of lead aptamer […]

December Newsletter – Aptamers in Flow Cytometry

In The December Issue •  Aptamer Maturation: Improving Aptamer Performance •  NGS and Bioinformatics Services for Aptamer Selection •  Aptamers in Flow Cytometry Subscribe to the monthly Base Pair e-newsletter Aptamer Maturation: Improving Aptamer Performance A key advantage of aptamers is the ability to select aptamers in vitro for binding to difficult (non-immunogenic, toxic) targets. […]

November Newsletter – Selecting Aptamers to Cells for Biomarker Discovery

In The November Issue •  Next Gen Sequencing for Aptamer Selection •  Bioinformatics Service for Aptamer Selection •  Selecting Aptamers to Cells for Biomarker Discovery Subscribe to the monthly Base Pair e-newsletter   Next Gen Sequencing for Aptamer Selection The introduction of next generation sequencing has enabled the analysis of millions of potential aptamer sequences […]

October Newsletter – Aptamers in Drug Delivery, Pharmacokinetics, and Dosing

In The October Issue Determining Aptamer Affinity Coming Soon! Next Generation Sequencing and Bioinformatics Services Aptamers in Drug Delivery, Pharmacokinetics, and Dosing   Determining Aptamer Affinity Did you miss the latest article from Base Pair? There are several popular methods for measuring biomolecular interactions and evaluating aptamer affinity. This article gives an overview of SPR, […]

September Newsletter – Aptamers for Canine Biomarkers, Opioid Detection, and High Resolution Microscopy

In The September Issue Aptamers to Canine Cancer Biomarkers Environmental Opioid Detection Aptamers in High Resolution Microscopy   Aptamers to Canine Cancer Biomarkers Comparative oncology is the study of naturally-occurring cancer in animals to identify treatments that can be applied to humans. Many types of cancer, including several types that are identical to human cancer, […]

August Newsletter – Label-free, One-step Detection with Aptamers

In The August Issue Monitoring Herbicide Residue with Aptamers Aptamer Workshop at Biosensors and Bioelectronics Label-free, One-step Detection with Aptamers   Monitoring Herbicide Residues with Aptamers The selection and application of herbicide can have a significant impact on crop yields. With the advent of targeted herbicides designed for resistant crops, the control of herbicide application […]