December Newsletter – Aptamers in Flow Cytometry

In The December Issue •  Aptamer Maturation: Improving Aptamer Performance •  NGS and Bioinformatics Services for Aptamer Selection •  Aptamers in Flow Cytometry Subscribe to the monthly Base Pair e-newsletter Aptamer Maturation: Improving Aptamer Performance A key advantage of aptamers is the ability to select aptamers in vitro for binding to difficult (non-immunogenic, toxic) targets. […]

November Newsletter – Selecting Aptamers to Cells for Biomarker Discovery

In The November Issue •  Next Gen Sequencing for Aptamer Selection •  Bioinformatics Service for Aptamer Selection •  Selecting Aptamers to Cells for Biomarker Discovery Subscribe to the monthly Base Pair e-newsletter   Next Gen Sequencing for Aptamer Selection The introduction of next generation sequencing has enabled the analysis of millions of potential aptamer sequences […]

October Newsletter – Aptamers in Drug Delivery, Pharmacokinetics, and Dosing

In The October Issue Determining Aptamer Affinity Coming Soon! Next Generation Sequencing and Bioinformatics Services Aptamers in Drug Delivery, Pharmacokinetics, and Dosing   Determining Aptamer Affinity Did you miss the latest article from Base Pair? There are several popular methods for measuring biomolecular interactions and evaluating aptamer affinity. This article gives an overview of SPR, […]

September Newsletter – Aptamers for Canine Biomarkers, Opioid Detection, and High Resolution Microscopy

In The September Issue Aptamers to Canine Cancer Biomarkers Environmental Opioid Detection Aptamers in High Resolution Microscopy   Aptamers to Canine Cancer Biomarkers Comparative oncology is the study of naturally-occurring cancer in animals to identify treatments that can be applied to humans. Many types of cancer, including several types that are identical to human cancer, […]

August Newsletter – Label-free, One-step Detection with Aptamers

In The August Issue Monitoring Herbicide Residue with Aptamers Aptamer Workshop at Biosensors and Bioelectronics Label-free, One-step Detection with Aptamers   Monitoring Herbicide Residues with Aptamers The selection and application of herbicide can have a significant impact on crop yields. With the advent of targeted herbicides designed for resistant crops, the control of herbicide application […]

July 2018 – In Vivo Imaging with Aptamers

In The July Issue Meet with Pair in Boston Base Pair Welcomes Garam Lee In Vivo Imaging with Aptamers   Meet with Base Pair in Boston Coming to Boston for the Bioprocessing Summit August 13-17? Set up a meeting with a Base Pair aptamer specialist to learn more about aptamers for process optimization / small molecule […]

June 2018 – Aptamers for LFA

In The June Issue Enhancing Aptamer Stability Base Pair Welcomes Paula Porter Aptamers for LFA (lateral flow assays)   Enhancing Aptamer Stability Did you miss the recent article on aptamer stability? Read the full article at the new Aptamer Stability page. Aptamer stability is an important issue when selecting aptamers for serum-based diagnostics, in vivo […]

March 2018 – Immunohistochemistry with Aptamers

In The March Issue The Importance of Negative Aptamer Selection (Counter Selection) Sample Preparation for Mass Spectrometry Survey Apta-histochemistry? Enhanced Tissue Analysis with Aptamers   The Importance of Negative Aptamer Selection Aptamers are DNA- or RNA-based ligands capable of selectively binding practically any molecular target.  At Base Pair, final aptamer sequences are selected from a […]

February 2018 Newsletter – Aptamers for Affinity Purification

In The February Issue: New Survey: Sample Preparation for Mass Spectrometry Two New Scientists Join Base Pair Aptamers for Affinity Purification   New Survey: Sample Prep for Mass Spec   Base Pair is currently developing aptamer-based pull-down assays for purification or depletion of specific analytes. We’d like to learn more about current challenges in sample […]