Human cytomegalovirus, HCMV, is a herpesvirus that infects between 50 to 85% of adults by the age of 50. Though most people do not show symptoms of disease, HCMV is a major cause of morbidity in AIDS and organ transplant. There is currently no vaccine and no cure for HCMV. Pp65 is the primary protein involved in evasion of host immune response in HCMV infection. It has been shown to prevent recognition by the immune system, to interfere with synthesis of immune components, and to inhibit natural killer cell cytotoxicity. HCMV glycoprotein gB is a fusion protein involved in HCMV viral entry.

John Paul Tomtishen III, (2012) Human cytomegalovirus tegument proteins (pp65, pp71, pp150, pp28). Virology Journal. 9:22.

Paul T. WilleTodd W. WisnerBrent RyckmanDavid C. Johnson, Human Cytomegalovirus (HCMV) glycoprotein gB promotes virus entry in trans acting as the viral fusion protein rather than as a receptor-binding protein,

ATW0058 CMV pp65 Aptamer Ordering Page

ATW0058 CMV pp65 Aptamer Data Sheet

ATW0043 CMV gB Aptamer Ordering Page

ATW0043 CMV gB Aptamer Data Sheet

ATW0044 CMV gB Aptamer Ordering Page

ATW0044 CMV gB Aptamer Data Sheet