ATW0046 - CLIC1 Aptamer

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Target:   CLIC1 (Chloride Intracellular Channel 1)

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   42.7 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

*Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

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Chloride intracellular channel protein 1, CLIC1, is found primarily in the nucleus and nuclear membrane. It can insert into membranes to form chloride ion channels. Membrane insertion is redox-dependent (occurring under oxidizing conditions) and channel activity is pH-dependent. CLIC-1 is involved in the regulation of cell cycle. []

View CLIC1 Aptamer Data Sheet

ATW0046 CLIC1 Aptamer Data Sheet [Download]