ATW0057 - CD63 Aptamer

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Target:   CD63

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   29.9 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

*Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

Base Pair Biotechnologies, Inc. does not collect VAT, import taxes, tariffs, duties, or other taxes, which are the sole responsibility of the purchaser.

CD63 is a tetraspanin, a cell surface-associated membrane protein with four transmembrane domains. CD63 interacts with integrins, cell surface receptors, kinases, and many other proteins. Cell surface expession of CD63 is highly regulated. While CD63 is involved with HIV-1 entry into T-lymphocytes, decreased surface expression of CD63 is associated with an increase in cancer invasiveness and metastasis.

Pols, M.S., et al. (2009) Trafficking and function of the tetraspanin CD63. Exp Cell Res. , 15,315(9):1584-92.

View CD63 Data Sheet

ATW0057 CD63 Data Sheet [Download]