ATW0081 - CD45 Aptamer

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Target:   CD45 (protein tyrosine phosphatase)

Target Species:   human

Target Type:   protein

Affinity Constant (Kd):   9.7 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

*Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

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CD45, also called lymphocyte common antigen, is a membrane glycoprotein. The intracellular region has protein tyrisine phosphatase activity. CD45 is involved in hematopoietic cell differentiation and T cell activation.

Altin, J.G., et al. (1997) The role of CD45 and CD45-associated molecules in T cell activation. Immunol. Cell. Biol. 75(5):430-45. and Nakano, A. et al. (1990) Expression of leukocyte common antigen (CD45) on various human leukemia/lymphoma cell lines. Acta. Pathol. Jpn. 40(2):107-15.

View CD45 Aptamer Data Sheet

ATW0081 CD45 Data Sheet [Download]