ATW0090 Aptamer to Phosphorylated pERK2 Thr183 (aa 171-189) Peptide
ERK2 (Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2) is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases.
This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and phosphorylated 183 ERK2 (aa 171-189) peptide CVADPDHDHTGFL(t)EYVATR as a target