ATW0090 - pERK2 peptide Thr183 (aa 171-189) Aptamer

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Target:   ERK2 (aa171-189) Phospho aa183

Target Species:   multi-species

Target Type:   peptide

Affinity Constant (Kd):   7.7 nM

Default 3' Linker (Spacer) is 10T. Please submit a custom quote request for other options.

*Please note that aptamers have much lower molecular weights than antibodies. Thus, there are typically five to fifteen times as many moles or molecules of aptamers present in a solution containing an equal mass. For example, 100 micrograms of an aptamer is equivalent to 0.5 to 1.5 mg of antibody, depending on the particular aptamer.

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Image courtesy of Ctr for Study of Systems Biology at Georgia Tech

ATW0090 Aptamer to Phosphorylated pERK2 Thr183 (aa 171‰-189) Peptide

ERK2 (Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2) is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases.

This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods and phosphorylated 183 ERK2 (aa 171-189) peptide CVADPDHDHTGFL(t)EYVATR as a target